Waynesburg, Pennsylvania welcomes you with a host of charming amenities often found in more densely populated areas. As the county seat, Waynesburg is home to the Greene County government, human services and the judicial system. The rural lifestyle is flavored by the past and reflects the agricultural and mining heritage of this area. Yet, with I-79, one is minutes from Pittsburgh and major league sports, cultural events, world-class medical care and the urban experience.